An evolutionary inherent aptitude that relies on levulose within the brain could ride the development ofAlzheimer ’s disease , according to a new subject . The results suggest that diet could be influencing the onset of the disease as a event of a foraging inherent aptitude , and that uniform fructose intake may be stimulating Einstein activity that results in nerve cell death and pathologic protein accretion .
“ We make the lawsuit that Alzheimer ’s disease is tug by dieting , ” said the work ’s tether generator Richard Johnson in astatement .
The idea focuses around a mechanics that triggers in the brain during period of scarcity , stimulating our body into foraging for food to supplement our dietetical need .
“ A basic tenet of life is to secure enough food , water and O for endurance , ” compose the author in the study .
“ Much attending has focused on the acute survival response to hypoxia and starving . However , nature has evolve a cagy way to protect animals before the crisis actually occur . ”
When human are downcast on food , a forage replete flush in to get them to focus on the important thing . Impulsivity and risk - taking goes up , and our memory and time - keeping get suppressed while our mind ration resource . levulose power this dampening – as fructose is metabolized , the forage instinct is increased and we can go on to front for resources .
It all sounds quite useful , except world do n’t really scrounge anymore and too much fructose can lead to some big problems . The researchers state that fructose metabolic process was link up to reduced stemma flow to areas of the brainiac involved in self - control , while it increase blood pass away to the food for thought reinforcement area , further boosting the forage response .
So , what come about when the brainiac develop too much of a near thing ? The team believe our mental capacity may have become stuck in the “ on ” position , with constant fructose metamorphosis lead in redness .
“ We trust that ab initio the fructose - dependant reduction in intellectual metabolism in these regions was two-sided and meant to be beneficial , ” Johnson continue . “ But continuing and dour reduction in cerebral metabolism aim by repeated fructose metabolism leads to reformist brain atrophy and nerve cell loss with all of the features of [ Alzheimer ’s ] . ”
laevulose in the Einstein has been linked to a number of morbid problems , including the buildup of Alzheimer’s - associate proteins .
“ A subject area discover that if you keep laboratory rats on fructose long enough , they get tau and amyloid beta proteins in the head , the same proteins seen in Alzheimer ’s disease . you could find oneself mellow fructose level in the brains of people with Alzheimer ’s as well , ” Johnson add .
This is very other research and the study urges for importantly more probe into any fructose – Alzheimer ’s disease link , but it could help change therapeutic and guide dietetic guidelines in the futurity if supported by further data .
The study was published inThe American Journal of Clinical Nutrition .
