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This Research in Action clause was furnish to LiveScience in partnership with the National Science Foundation .
Just as images of coltsfoot let out fresh detail about space , this trope of a nucleus reveals fresh details about the cell . The green and chicken back breaker mark the position of telomeres , caps on the goal of each chromosome . Until recently , scientist thought that the primary task of telomere was to keep chromosome from fraying . young research that shows telomere motivate to the out edge of the nucleus suggests that these roof also may play a role in prepare DNA after cell divide .
telomere are repeat of the same sequence of DNA building blocks . In masses , telomere consist of the sequence TTAGGG repeated around 2,000 times . An enzyme called telomerase sum more of the TTAGGG sequence to chromosome close , help the telomeres keep their length . This is important in a growing foetus , for example , where cells are dividing rapidly .
Most adult body cellular telephone , however , keep telomerase tightly control and not very active . As this materialize , telomeres eventually shorten . When they have shrivel to a certain length , the cells can go into retirement and end dividing . Cancer cells , on the other hand , often increase their levels of telomerase so they can divide indefinitely .
Wanting to good understand the role of telomeres during cellphone class and other portion of the cell cycle , researchers at theSalk Institute for Biological Studiestracked telomere movement in real - time . They labeled telomere in living human mobile phone with molecules that glowed and then used advanced sentence - lapse resilient - cell microscopy to follow the movement for at least 20 hour . The results showed that telomere move to the periphery of the cell ’s nucleus follow cadre partitioning . Two proteins seem to tether the telomeres there .
While the implication of this spatial move are not yet clear , the researcher suspect that the repositioned telomere may serve as anchor points for reorganize chromosomes and regulating cistron expression after cells have duplicated . They also speculate that the process might play a role in maintaining telomeres . The scientist plan to explore these possibilities in future experiments .
This research was supported by the National Institutes of Health . To see more double and picture of basic biomedical research in activity , visitNIH ’s Biomedical Beat Cool Image Gallery .
